My dwarf fortress reflex makes me try and kill as many zombies as it possible on 1 tile, then I butcher them all, grab what I want and light the rest on fire.
The cbm flamethrower is great for raging fires (couple of hipflasks full of petrol work as well), but if you really do want to destroy everything then acid is probably the only way to go, bit of a hassle though.
Generally though, just move on. Take what you want, pile 1 of every useful tool in a trunk in your car then leave the rest.