This is a mod that blacklists Hulks and Brutes of any variety.
I’ve never used it myself, so I don’t know how well it works, or if there are compatibility issues.
When you’re creating a world, and are at the mod selection screen, Tab (usually above Caps Lock) lets you move between mods that add content, mods that blacklist creatures and possibly items, and mods that change the balance of the game.
Classic Zombies should turn off all zombies except “Zombie”, and will disable some buildings, like the Lab, I believe. It may also affect zombified wildlife.
Nailboard traps are the best way to deal with Brutes early on. Make 9 of them (180 nails, 27 two-by-fours, and something with hammering 1, a rock or chunk of steel will suffice), then lay them in a square, and walk the Brute through them until it kills itself. It also works with Shocker Zombies, but you will be shocked a few times. I’ve never successfully used it against Shocker Brutes or Hulks, though. A great many enemies are vulnerable to this tactic, including robots like the Tribot, or Riot Control Bot, but it is decidedly inefficient against Tank Drones.
As a bonus, any enemy that has a sense of self preservation, such as Mi-Gos, Grackens, or Scientist Zombies won’t step on Nailboard Traps, so you can surround yourself with eight of them, one on every adjacent square, and they won’t be able to attack you. Then, if you have something with a reach attack, like the Knife Spear, you can safely attack them until they are dead or fleeing.