Negative mutations are inevitable when you foray into genetic modification - play with fire, bound to be burned. But, are they all that bad? Some of them can be a lot of fun, forcing you to play in a unique or at least notably different way; some of them might not even be ‘bad’, depending on how you work them. So, what are your favorites?
My top three, in no particular order, are:
Heat Dependent -> Ectothermic
I think Carnivore especially adds a fun challenge to the game, and makes me feel more attached to my character from a role play aspect (since I now need to think about what they can actually eat, and how to acquire more, plus it moves me towards new goals like learning to can/preserve meats, and actively hunting out animals).
Heat Dependent I like for similar role play reasons; it mixes things up not only in combat but also in normal play, and can actually end up benefiting you for packing on clothing outside of winter.
Animal Discord is a bit less personal; I just think it’s fun to see beavers and lemmings and whatnot run up like they wanna act tough, it’s a funny idea to me.