i’m really thinking the 30 Days Of Night vampires; basically it’s just a virus that kills you and reanimates you as the undead, immortal, strong and fast but you need human blood to keep those advantages, other wise you’re just undead, immortal, but weak and slow. once NPCs have been figured out and unbugged maybe the player could feed on them, but for now vampirism would have to be something you DO NOT want to catch.
maybe make vampires insta-death at melee range, since they are starving for lack of human blood and would therefore be slower than a zombie.
as for curing it, ok maybe not antibiotics, but how about Purifier? that would fit lore-wise because vampirism is basically a super mutation. maybe depending on how starved you are and how long you’ve been a vampire it’ll require multiple dozes over a period of time, meanwhile you’re loosing your precious positive mutations. perhaps each dose of purifier you take reduces vampirism by a % but you can only use one once per day or week or something, but if you wait too long between doses then you will start to loose ground.