Grin… OK >besides< that.
I use saves heavily to try different things and learn the game. Using it to perfectly stack every good mutation under the sun though, for me that wouldn’t be fun.
For example you can try to get hard / risky mutations you want first, because you can easily purify back to square one and try again.
Once you have some good mutations, it’s tricky. Currently I try to make small changes at a time, and if I get a bad effect: add a couple more mutations and then purify (drinkable version, not the stronger serum). Because purify will remove more than one thing, and it seems to like removing the more recent changes first (sometimes…).
I’m still trying to figure it out.