Haven’t run out of space, no, nearly 200GB free on both OS and Secondary drives.
I was able to enable autopickup from the main menu with no errors, even added some items to auto-pickup as well.
…I hate bug hunting. After testing the above and saving/quitting, I disabled autopickup from the main menu and reloaded my game. Enabling autopickup from inventory now works as expected with no errors that I can tell at the moment.
Sorry for the wild goose chase, I’ll keep an eye on it.
Only thing related I can come up with is that this was the first attempt to use Autopickup since I started this version. Maybe if it doesn’t have autopickup enabled via menu at least once, the inventory shortcut crashes?
This is why i’m not paid to be a bug tester, lol. Sorry again.