For a novice player seeking to survive the early game, Str>=11, Dex>=9, 11 in Per and whatever you wish in Int. Str will grant you ability to survive melee and finish opponents quicker, Dex will help you hit the opponents if your skills are too low or you have torso encumbrance, and Per will help you not wander into minefields even if there’s sunlight glare. Int is important for shortening the time to get skills up, but your char will quickly die anyway, so that’s not a problem. Obviously, scoundrel/survivalist profession, cheaty traits like truth teller or ugly, and don’t forget about fleet-footed to ease the things. Again, you’ll die anyway, but this setup is the easiest to learn.
For an advanced player seeking an easy mid-late game, 13/11/12/10, negative traits to max, a couple of positive traits, no skills and a profession on the cheaper side, or even a negative one like shower victim, if you are confident in your early-game survival capabilities. Str is useful overall, as it will ease early-game melee and late-game weight carrying problems. Dex initially sucks, but will become more important when you start actively using long-range weaponry. 10 Per will allow you to see nearly all traps if you’ve got glare protection on. 12 Int is super-important for reducing the grind, as book-grinding, car-dismantling and electronics assembly/disassembly for upping the skills is the most boring thing in the game.
For a roleplayer or an expert, all bets are off. For example, 4/4/4/4 (aka a child) is godawful, but can be salvaged with a really careful game and lucky finds like a gun-nut basement. Shotguns are nearly an only possibility to dish out damage, as you won’t be able to hit shit with anything else thanks to dex and per. If you want to make this stuff at least a bit easier, go fleet-footed/parkour/quick to run away from most scary things and don’t forget about addiction resistant, because pills will frequently save your bacon. Plus, you’ll have an unforgettable mental image of a cocaine-snorting, meth-fueled kid pummeling hordes of zombies with a Saiga (essentially, a kalashnikov firing 12-gauge, the only magazine-fed shotgun in the game). Enjoy.