Have you ever seen the animated film Ghost in the Shell? or read the manga Battle Angel Alita?
Both of these explore the idea in their own way, both from the perspective of characters with almost entirely cybonetic bodies.
Now I’m neither for or against this “Cyberpsychosis”, I don’t have a background in Shadowrun so I don’t really know how far they take it but it’s been a common thing for humans to discuss stuff like “What is human?” etc for… well for about as long as we’ve been writing stuff down and the question of how cybonetic you can be and still be human almost as long as sci-fi has been a genre.
My point is, even if “Cyberpsychosis” isn’t a fit for Catacysm, something in a similar vein could be and it would be worth discussing.
And just for the record, you can see here where I fall on this whole meta discussion: