Not yet, but that’s why I have a project set up to track progress toward it https://github.com/CleverRaven/Cataclysm-DDA/projects/10.
A little optimization here, a little scene culling there, and before you know it we could get there, or at least reasonably close.
It’s pretty likely we’ll end up only being able to load a 300x300 area or so (5x bigger than it is now), but the rest will be made up by the planned sniping feature, where you dynamically load surroundings when you aim at something outside the reality bubble.
It’s all pretty far off, but I don’t see a reason it couldn’t work.