Yeah; they begin gazing at you (as far as I can tell) as soon as they enter the reality bubble, and their gaze attack levels everything instantly no matter how well fortified it may be, so the only thing you can do to stop them from messing up your stuff is avoid having it between the eye and your character. Ceiling collapsing is annoying and instantly destroys your cargo carrier if you have one, vehicle destruction is hair-pullingly awful, teleglow usually ends up giving you a fungal parasite, and killing them appears to have gotten much more irritating at some point in development.
Monsters that just threaten the player’s health are dangerous, but monsters with the power to instantly destroy everything they’ve spent hours creating threaten their sanity.