You don’t have to go Freakishly Huge to pass the thresholds, though that’s only if you’re not strong in any other category. Even then, just remove the roof where you’ll be sitting and you’re fine, I think. Still, the biggest problem will be the inability to wear normal clothing, which may be gamebreaking if you’re not prepared with a lot of XL stuff. Even then, you’ll never achieve the potential you could’ve achieved.
Anyway, if you want the most strength possible, Extremely Strong and Inconveniently Large/Large should do it, unless you took 4 strength at the beginning you really don’t need those extra 3 points that Insanely Strong and Huge give you. I’m strength based myself, and I did fine without even Large.
As for turtling/tanking, both Cattle and Bear thresholds contain Resilient, Solidly Built and TAAANK, so if you’re really hurting for health, go with those. If you’re hurting for nourishment, go with the Plant thresholds, which lets you get a lot of stuff just from being on dirt/diggable ground.
The hoarding bit really doesn’t need many mutations, or even equipment - just the ability to dispatch whatever comes your way while you’re looting, which can be done with skills alone if you’re godly enough. Though to enhance it I’d definitely go with a few very careful Bird mutagens to get Road-Runner, and if you can handle the weight loss, Light/Hollow bones.
I’m a travelling hoarder myself, got myself a rolling fortress, and the way I went was actually Ursine pre-thresh for Extremely Strong and the various other ursine bits that help in little ways, Bird for road-runner, Plant for Bark and Vine Limbs, and Elf-a for all the other Extreme stats. As far as I’m concerned, I’m basically invincible in streets, filled with 0.01 evolution 2.0 spawn monsters. Though that is with skills.
In other words, don’t rush a threshold. You can do without one for a long time.
