Roleplay wise, I use mutagens to try become the ‘new human race’
The world has gone to shit, a generic human by itself can’t survive without equipment of some kind, most humans are already dead. But you come across a book detailing the ability to mutate.
The word mutate instantly gives bad impressions, but it’s actually another word/form of evolution. Pressed in to a corner, you decide to evolve in to a super human, cooking up mutagens and purifies to try and find the perfect mix.
I limit myself to only a few things that are noticeable yet helpful (bird wings, retractable claws for example) but I’ll try to get plenty of mutations that another person would not see were obtained from mutating, such as trait like mutations (glorious, deft) or the unnoticeable kind (web walker, night vision.)
Next thing you will need are other humans, males or females, to create offspring, the Adam and Eve of your new human race! Remember to have a safe place to keep your new harem, going out with your family is a much more dangerous affair than it used to be!
Obviously however, you must make sure not to ‘break the threshold’ and become too much of one particular thing. For example, if you’re taking a Feline mutagen, if you break the threshold, you’ll no longer be a human with a few feline traits, you’d be more feline with a couple of human aspects, making it impossible for you to reproduce with other humans as you’re far too gone.
I suppose you could find a cat or two though…