Partially yes.
You can't hit smoker zombies with projectile weapons.
I swear I remember hitting them with projectile weapons in the experimentals… Not always but I’m sure I managed it a few times. Unless I’m getting confused with skeletons. Anyway, couldn’t hit the bastard in melee either despite not really having any encumberance to speak of at the time. (This character didn’t have a backpack or vest. Just clothing and a rifle.)
Watch your encumbrance level.
Watch your pain level, for gods sake.
Well, I think I was only on 1 pain when I mysteriously stopped being able to hit zombies. Also encumberance shouldn’t have been super high. I mean OK I had an armoured vest and backpack on but I killed some zombies like that before finding my attacks were missing continously.
Maybe the random number generator decided I’d had enough lucky rolls already.
It’s certainly being a dick to me regarding finding guns.