Got chemical imbalance due to genetically unstable. Took a purifier immediately and removed the mutation (plus some others I didn’t want to remove). So far, my character has been permanently at very cold. On the other hand, it seems more like an error since I’m not getting morale penalties and other effects. Temperature is normal, but it just says very cold (and rising) for several hours now.
Similar happened to me once in 0.B.
Because of a Reptilian Muzzle mutation, i was unable to protect the character’s mouth against the cold. After got Chemical Imbalance i purified the mutations, but stuck with the Chilly (Rising!) status for 11 days. With some clothes i got the warm status, but never comfortable.
On 11. day got Chemical Imbalance again, chilly changed to very cold, but after i purified the Chemical Imbalance the body temperature changed back to comfortable.
Ahhh, so that’s what it was!
http://smf.cataclysmdda.com/index.php?topic=9520.0