Yes, but if they are massive dicks people are just going to ignore or exterminate them rather than trying to interact. You can make them a bit arrogant, but much farther than that will defeat the entire point of making it possible to interact with them, because no one will bother.
And aren’t all the other factions either unequivocally hostile or too alien to be communicated with? The fungus has to assimilate you, and at that point you basically become their meat puppet. The blob flat out cannot be interacted with, and getting its attention would be a horribly retarded idea per Kevyn. The netherworld creatures like the Mi-Go are all evil and hostile or nonsapient.