I mean, that goes against established lore. Not just lore that’s discussed out of universe, but stuff you can find on the Lab Notes and see in action with the Bionic Zombies. Mutation takes into account foreign objects embedded in the body, which is why you get Shockers, Shocker Brutes, Bio-Operators…
This doesn’t make much sense either, IMO, because they’re still nervous signals. They still work the exact same way, though they’re a bit different.