If you are tired of trial and error, Vormithrax has a great beginner tutorial series on YouTube. I’d say the basics would be… controlled fire, and confidently sourcing food and water?
( construct brazier/find oven or stove, scavenge houses or search bushes in the woods for food )
I have tried pretty much every tile-set out there and still use ASCII 99% of the time. I feel like, at least in my experience, once you’ve gotten used to the classic ASCII roguelike pseudographical style, it actually feels like a handicap to switch to tiles. Much harder time in accurately gauging exact spacing and object recognition ( probably that wouldn’t be that big a deal if I used a particular tileset til greater familiarity ).
On a similar note, I also find the vi-style directional keys to be much nicer to use ( but harder to learn ).
Obsessively tinkering with fonts is also an OCD thing I seem to find myself doing all the time… shrug
My typical arrangement: