I just really like playing with low item/vehicle spawn rates, high enemy spawn rates and with a start about a week after the “day 0”.
That makes melee builds really, REALLY dicey: Z’s are numerous and advanced from the start, and disinfectant is quite VERY rare (unless RNG favors you). But it really just exemplifies the fact that melee builds are essentially “much higher risk, much faster zombie killing”. While ranged are much, much more reliable, but less powerful in early game.